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- 031-290-7783
- jhjeong@skku.edu
- 약학관 6층 530627호실
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관심분야
Polymer-based drug delivery systems for biological molecules Stem cell engineering and therapy Solubilization of poorly water soluble drugs
학력
- Ph.D. KAIST (2003)
약력/경력
- 2007~ : Assistant and Associate Professor, Sungkyunkwan University
- 2004~2007 : Postdoctoral Research Associate, University of Utah
- 2003~2004 : Postdoctoral Fellow, KAIST
학술지 논문
- (2023) Alveolar macrophage phagocytosis-evading inhaled microgels incorporating nintedanib-PLGA nanoparticles and pirfenidone-liposomes for improved treatment of pulmonary fibrosis. BIOACTIVE MATERIALS. 33, 1
- (2023) Highly Prolonged Release of the Cancer Vaccine and Immunomodulator via a Two-Layer Biodegradable Microneedle for Prophylactic Treatment of Metastatic Cancer. BIOMACROMOLECULES. 24, 3
- (2023) Chemoattractant releasing microneedles for enhanced DNA vaccination. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY. 117, 1
- (2022) Delivery of self-replicating messenger RNA into the brain for the treatment of ischemic stroke. JOURNAL OF CONTROLLED RELEASE. 350,
- (2022) Nanomicelle-generating Microneedles Loaded With Tranilast for Treatment of Hypertrophic Scars in a Rabbit Model. IN VIVO. 36, 4
- (2022) Microneedle-Directed Drug Delivery to Tumor-Draining Lymph Node for Synergistic Combination Chemoimmunotherapy for Metastatic Cancer. ADVANCED THERAPEUTICS. 5, 4
- (2022) Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation. SMALL. 18, 15
- (2021) Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines Against COVID-19. ACS NANO. 15, 9
- (2021) Hyaluronic Acid Coating on Hydrophobic Tracheal Scaffold Enhances Mesenchymal Stem Cell Adhesion and Tracheal Regeneration. TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 18, 2
- (2021) Toxico-metabolomics study of a deep eutectic solvent comprising choline chloride and urea suggestsin vivotoxicity involving oxidative stress and ammonia stress. GREEN CHEMISTRY. 23, 3
- (2021) Human Ferritin Platform and Its Optimized Structures to Enhance Anti-Cancer Immunity. ADVANCED THERAPEUTICS. 4, 2
- (2020) Enhanced Cancer DNA Vaccine via Direct Transfection to Host Dendritic Cells Recruited in Injectable Scaffolds. ACS NANO. 14, 9
- (2020) Microporous Organic Nanoparticles Anchoring CeO2 Materials: Reduced Toxicity and Efficient Reactive Oxygen Species-Scavenging for Regenerative Wound Healing. CHEMNANOMAT. 6, 7
- (2020) Insights into the Vastly Different Effects of Eutectic Solvents on the Stability of Phenolic Compounds. JOURNAL OF PHYSICAL CHEMISTRY LETTERS. 11, 13
- (2020) Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain. BIOMATERIALS SCIENCE. 8, 11
- (2020) Development of microRNA-21 mimic nanocarriers for the treatment of cutaneous wounds. THERANOSTICS. 10, 7
- (2020) Degradation-regulated architecture of injectable smart hydrogels enhances humoral immune response and potentiates antitumor activity in human lung carcinoma. BIOMATERIALS. 230,
- (2019) Simultaneous delivery of DNA vaccine and hydrophobic adjuvant using reducible polyethylenimine-functionalized graphene oxide for activation of dendritic cells. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY. 80, 1
- (2019) Effective systemic siRNA delivery using dual-layer protected long-circulating nanohydrogel containing an inorganic core. BIOMATERIALS SCIENCE. 7, 8
- (2019) Enhanced Transfection of Human Mesenchymal Stem Cells Using a Hyaluronic Acid/Calcium Phosphate Hybrid Gene Delivery System. POLYMERS. 11, 5
단행본
- (2009) 약제학요점. 신일북스. 공동
- (2009) 생체재료학. 자유아카데미. 공동
- (2009) 제제학 (의약품제형과 약물전달시스템). 도서출판 신일북스. 공동
특허/프로그램
- 체세포 직접교차분화 유도 나노입자의 제조방법 및 이의 용도(A Method for preparing nanoparticles inducing direct conversion from somatic cells and use thereof). 10-1960-1700000. 20190313. 대한민국
- 자가 조립 나노입자 방출형 용해성 마이크로니들 구조체 및 그 제조방법(Dissolvable microneedles structure releasing self-assembled nanoparticles and method for preparing same). 10-1956-4440000. 20190304. 대한민국
- 카테콜기를 포함하는 유기화합물로 개질된 친수성 고분자를 이용한 칼슘 포스페이트 나노 복합체 및 그 제조방법. 10-2014-0108520. 20171221. 대한민국
- 생체모방물질을 이용한 칼슘포스페이트 나노입자 제제. 10-2013-0007675. 20141120. 대한민국
- 카데콜기를 포함하는 유기화합물로 개질된 친수성 고분자를 이용한 칼슘 포스페이트 나노 복합체 및 그 제조방법. 10-2013-0007675. 20141120. 대한민국
- 수난용성 약물을 내부에 포함하는 알부민 나노입자 제조방법. 10-2012-0009253 . 20141022. 대한민국
- 고효율 유전자 전달을 위한 항산화성 고분자 미셀제제. 10-1023-0079604. 20140225. 대한민국
- 미셀을 주형으로 이용한 금 나노입자의 제조방법(A method for manufacturing dendritic gold nanoparticles using antioxidative micelles as a template). 10-1362549-0000. 20140206. 대한민국
- 폴리에틸렌이민 및 담즙산으로 구성되는 세포막융합활성을 지닌 양친성 고분자 회합체. 10-1128108. 20120312. 대한민국
학술회의논문
- (7013) Reduced cellular oxidative stress by antioxidative polymeric micelles directed to enhanced gene transfection. The 7th World Congress on Biomimetics, Artificial Muscles and Nano-Bio. 대한민국
- (2023) Tailoring Liposomal Membrane Elasticity for Enhanced Biodistribution and Anti-Imflammatory Responses in Systemic Rheumatoid Arthritis Treatment. ESB2023. 스위스
- (2020) Repositioning dihydroergotamine on sepsis with self-assembled PEGylated human serum albumin nanocarrier. 2020년 한국생체재료학회 추계학술대회. 대한민국
- (2020) Hyaluronic acid / calcium phosphate hybrid gene delivery system promotes osteogenic differentiation of human mesenchymal stem cells. 2020 한국공업화학회 학술대회. 대한민국
- (2020) Improvement of gene silencing and development of siRNA delivery by dendritic gold nanoparticle. 2020 한국공업화학회 학술대회. 대한민국
- (2020) Suppression of tumor growth via systemic siRNA delivery with bioreducible bile acid-conjugated PEI. 2020 한국공업화학회 학술대회. 대한민국
- (2020) Enhanced cancer chemo-immunotherapy using nanomicelles-generating microneedles containing paclitaxel and TLR7/8 agonist. 2020 한국생물공학회 추계학술대회 및 국제심포지움. 대한민국
- (2020) Enhanced systemic siRNA delivery to solid tumors by reducible bile acid conjugate polyethylenimine. 2020 한국생물공학회 추계학술대회 및 국제심포지움. 대한민국
- (2020) Repositioning dihydroergotamine on sepsis with self-assembled PEGylated human serum albumin nanocarrier. 2020 한국생물공학회 추계학술대회 및 국제심포지움. 대한민국
- (2020) Hyaluronic acid / calcium phosphate hybrid gene delivery system promotes osteogenic differentiation of human mesenchymal stem cells. 2020 한국생물공학회 춘계학술대회 및 국제심포지움. 대한민국
- (2020) Inhibition of metastatic melanoma through nano-micelle generating microneedles including doxorubicin. 2020 한국생물공학회 춘계학술대회 및 국제심포지움. 대한민국
- (2019) Therapeutic cancer vaccination using nanoparticle-releasing microneedles. IEEE International Conference on Nano/Molecular Medicine and Engineering. 대한민국
- (2019) Enhanced cancer immunotherapy using nanomicelle generating microneedles containing paclitaxel and TLR7/8 agonist. 한국약제학회 국제학술대회. 대한민국
- (2019) Rivoceranib drug re-positioning: developing new uses for anti-neovascularization via the regulation of tyrosine kinase signaling. 한국약제학회 국제학술회의. 대한민국
- (2019) Stabilized nanominerals for the targeted delivery of biomolecules. 한국공업화학회 추계학술대회. 대한민국
- (2018) GO nanoflakes fuctionalized with catechol-derivatized cationic polymer for efficient siRNA delivery. 2018 한국생체재료학회 추계학술대회 및 총회. 대한민국
- (2018) Intradermal co-delivery of plasmid DNA and hydrophobic adjuvant via dissolving microneedles for enhanced cancer theraphy. 2018 한국생체재료학회 추계학술대회 및 총회. 대한민국
- (2018) hMSC osteogenic differentiation using cap/catechol-HA gene delivery vector. 2018 한국생체재료학회 추계학술대회 및 총회. 대한민국
- (2018) Oral delivery of superoxide dismutase to treat acetaminophene-induced hepatotoxicity and liver disease using deoxycholic aicd-modified polyethylenimine. 2018 한국공업화학회 춘계 총회 및 학술대회. 대한민국
- (2018) hMSC using CaP/dopa/HA gene delivery for inducing osteogenic differentiation. 2018 한국공업화학회 춘계 총회 및 학술대회. 대한민국